Melbourne's long-awaited new contemporary art museum officially opened to the public this weekend, and early visitors are already describing it as "a once-in-a-generation cultural moment for the city."

The building itself, designed by a celebrated international architecture firm, is a striking composition of cantilevered concrete and sweeping glass that has divided critics in the best possible way.

Inside, the inaugural exhibition brings together over two hundred works from across the globe, including pieces never before displayed in the southern hemisphere.

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